MT-2, or Melanotan II, is a synthetic cyclic heptapeptide and a melanocortin-receptor agonist. It is a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH), studied in preclinical research within melanogenesis and pigmentation models. MT-2 does not occur as a discrete protein in the human proteome, which makes it a fully synthetic research compound.
As supplied for research, MT-2 is a lyophilized powder that is water-soluble on reconstitution and is handled as a research-grade material for in vitro and animal-model investigation only.
Verified dataVerified compound data
| Property | Value |
|---|---|
| Compound name | MT-2 (Melanotan II) |
| CAS number | 121062-08-6 |
| PubChem CID | 92432 |
| Molecular formula | C50H69N15O9 |
| Molecular weight | ~1024.2 g/mol |
| Amino acid sequence | Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 |
| Structure | Cyclic heptapeptide |
| Physical form | Lyophilized powder |
Data verified against PubChem (CID 92432) and ChemicalBook (CAS 121062-08-6).
MechanismResearch-context mechanism
In preclinical literature, MT-2 is characterized as a non-selective agonist at melanocortin receptors, with research interest in MC1R-mediated melanogenesis signaling and broader melanocortin-pathway activity. These mechanisms are described strictly in research models; they are not established human-use mechanisms.
Research summaryCurrent research summary
MT-2 appears in preclinical literature focused on the melanocortin system. Reported research areas include:
- Melanocortin-receptor (MC1R) agonism in pigmentation models
- Melanogenesis signaling studies
- Comparative melanocortin peptide-family research
Handling and reconstitution
MT-2 is supplied as a lyophilized powder. Reconstitute per your laboratory protocol with a suitable diluent such as a suitable sterile solvent, introduced gently down the vial wall, and store lyophilized material refrigerated at 2-8 °C, protected from light and freezing. See our peptide reconstitution protocol for general lab-handling guidance.
Every lot of Vantage Aminos MT-2 ships with a batch-specific Certificate of Analysis (HPLC purity and mass-spectrometry identity), U.S. synthesized for research use.
For research use only. Not for human or veterinary use.
- HPLC + MS tested, every batch
- U.S. synthesized
- Batch COA on the product page
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