Selank is a synthetic heptapeptide (seven amino acids) based on the immunomodulatory peptide tuftsin, with a stabilizing Pro-Gly-Pro extension. It is studied in preclinical research as a tuftsin-fragment analog and tool compound for investigating neurochemistry in animal and cell-culture research models.
Selank is a fully synthetic analog and does not occur natively in this form. As supplied for research, it is a lyophilized powder that is water-soluble on reconstitution.
Verified dataVerified compound data
| Property | Value |
|---|---|
| Compound name | Selank (tuftsin Pro-Gly-Pro analog) |
| CAS number | 129954-34-3 |
| PubChem CID | 11765600 |
| Molecular formula | C33H57N11O9 |
| Molecular weight | ~751.9 g/mol |
| Amino acid sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP) |
| Length | 7 residues (heptapeptide) |
| Physical form | Lyophilized powder |
Data verified against PubChem (CID 11765600, C33H57N11O9, MW ~751.9) and ChemicalBook (CAS 129954-34-3, MW 751.87).
MechanismResearch-context mechanism
In preclinical literature, Selank is studied as a tuftsin-fragment analog. In animal and cell-culture research models, studies have examined its association with brain-derived neurotrophic factor (BDNF) expression and related neurochemical-signaling pathways. Research has also examined its interaction with neuropeptide-metabolism pathways at the gene-expression level in animal models. These mechanisms are described strictly in an in vitro and animal research-model context; they are not established human-use mechanisms, and no behavioral outcome is described or implied.
Research summaryCurrent research summary
Selank appears across preclinical literature as a tuftsin-fragment research tool. Reported research areas include:
- BDNF and neurotrophin gene-expression studies (animal models)
- Tuftsin-fragment receptor- and pathway-interaction studies
- Neurochemical-pathway research models (in vitro and animal)
- Peptide-stability studies (the Pro-Gly-Pro extension vs native tuftsin)
The existing body of work is predominantly in vitro and animal, much of it originating in research literature outside the United States. Selank is not an FDA-approved drug and has no established human therapeutic use. All framing here is strictly laboratory research.
QuestionsFrequently Asked Questions
What is Selank?
Selank is a synthetic seven-residue peptide based on the tuftsin fragment with a Pro-Gly-Pro extension, studied in preclinical BDNF-expression and neurochemistry research models. It is a research compound supplied as a lyophilized powder and is not approved for human use.
What is the molecular formula of Selank?
The molecular formula of Selank is C33H57N11O9, with a molecular weight of approximately 751.9 g/mol (PubChem CID 11765600).
What is the CAS number for Selank?
The CAS registry number for Selank is 129954-34-3.
What is the amino acid sequence of Selank?
The sequence is Thr-Lys-Pro-Arg-Pro-Gly-Pro (single-letter: TKPRPGP), a seven-residue peptide based on tuftsin (Thr-Lys-Pro-Arg) with a stabilizing Pro-Gly-Pro extension.
How is Selank stored and reconstituted in a research setting?
Lyophilized Selank is stored at 2 to 8°C, protected from light and humidity. It is reconstituted with a suitable sterile solvent, is water-soluble, and reconstituted material is held at 4°C and used within about 30 days, avoiding repeated freeze-thaw cycles.
Is Selank approved for human use?
No. Selank is not an FDA-approved drug and is not intended for human consumption. It is offered strictly as a research compound for laboratory use.
For research use only. Not for human or veterinary use. Not approved by the FDA. 21+
- HPLC + MS tested, every batch
- U.S. synthesized
- Batch COA on the product page
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