Both forms of CJC-1295 are synthetic analogs of growth-hormone-releasing hormone built on a modified GRF(1-29) sequence; the key research distinction is the Drug Affinity Complex (DAC) and its effect on half-life.
At a glance
| Property | CJC-1295 with DAC | CJC-1295 No DAC |
|---|---|---|
| Class | GHRH(1-29) analog + DAC | GHRH(1-29) analog (mod GRF 1-29) |
| Primary research target | GHRH receptor | GHRH receptor |
| Research half-life | Extended (albumin-binding) | Short (pulsatile) |
| Research domain | Sustained somatotropic signaling | Pulsatile GH-axis signaling |
| Format | Lyophilized powder | Lyophilized powder |
CJC-1295 with DAC in research
CJC-1295 with DAC incorporates a Drug Affinity Complex that binds serum albumin in research models to extend circulating half-life, supporting study of sustained GHRH-receptor signaling. See the full CJC-1295 with DAC research profile.
CJC-1295 No DAC in research
CJC-1295 No DAC (modified GRF 1-29) lacks the albumin-binding complex and is studied for short-duration, pulsatile GHRH-receptor signaling in growth-hormone-axis models. See the full CJC-1295 No DAC research profile.
Key differences
- The DAC modification extends research half-life via albumin binding; No DAC is short-acting.
- DAC supports sustained-signaling models; No DAC supports pulsatile-signaling models.
- Both target the GHRH receptor and share the GRF(1-29) backbone.
Selecting for a research model
Researchers select between the DAC and No-DAC forms based on whether a sustained or pulsatile GHRH-signaling profile fits the model. These distinctions are described strictly in the context of research models and are not statements of efficacy, safety, or suitability for any use.
Both CJC-1295 with DAC and CJC-1295 No DAC ship from Vantage Aminos with a batch-specific Certificate of Analysis (HPLC purity and mass-spectrometry identity), U.S. synthesized for research use.
For research use only. Not for human or veterinary use.
- HPLC + MS tested, every batch
- U.S. synthesized
- Batch COA on the product page
