Research use only. All compounds are for laboratory research. Not for human or veterinary use. 21+.

CJC-1295 (with DAC): What the Research Shows

Published June 17, 2026 · Research notes

By Vantage Research TeamReviewed against primary sourcesUpdated July 2026

CJC-1295 with DAC is a synthetic, long-acting analog of growth-hormone-releasing hormone (GHRH), built on a modified GRF(1-29) sequence and incorporating Drug Affinity Complex (DAC) technology that extends its research half-life. It is studied in preclinical research within the somatotropic axis and neuroendocrine signaling. In this modified form it is a fully synthetic research compound.

As supplied for research, CJC-1295 with DAC is a lyophilized powder, water-soluble on reconstitution, handled as a research-grade material for laboratory investigation only.

Verified data

Verified compound data

Property Value
Compound name CJC-1295 (with DAC)
CAS number 863288-34-0
Classification GHRH(1-29) analog with DAC
Molecular formula C165H269N51O50
Molecular weight ~3647.2 g/mol
Structure Modified 30-residue GRF analog + DAC
Physical form Lyophilized powder

Data verified against ChemicalBook (CAS 863288-34-0).

Mechanism

Research-context mechanism

In preclinical literature, CJC-1295 is characterized as a GHRH-receptor agonist; the DAC modification binds serum albumin in research models to extend circulating half-life, supporting study of sustained somatotropic-axis signaling. These mechanisms are described strictly in research models; they are not established human-use mechanisms.

Research summary

Current research summary

  • GHRH-receptor agonism studies
  • Somatotropic-axis and growth-hormone-secretion research models
  • Albumin-binding half-life-extension (DAC) studies

For the short-acting variant, see our CJC-1295 (No DAC) research profile.

Handling

Handling and reconstitution

CJC-1295 with DAC is supplied as a lyophilized powder. Reconstitute per your laboratory protocol with a suitable diluent such as a suitable sterile solvent, and store lyophilized material refrigerated at 2-8 °C, protected from light and freezing. See our peptide reconstitution protocol for general lab-handling guidance.

Every lot of Vantage Aminos CJC-1295 with DAC ships with a batch-specific Certificate of Analysis (HPLC purity and mass-spectrometry identity), U.S. synthesized for research use.

For research use only. Not for human or veterinary use.

All compounds described in Vantage Aminos research content are sold for laboratory and scientific research purposes only. Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any condition. For research use only.
  • HPLC + MS tested, every batch
  • U.S. synthesized
  • Batch COA on the product page
Available from VantageCJC-1295CJC-1295VA-CJC1295-5MG · Lyophilized Powder$89View compound