MOTS-c and 5-Amino-1MQ are both studied in metabolic research, but one is a mitochondrial-derived peptide and the other a small-molecule enzyme inhibitor with distinct targets.
At a glance
| Property | MOTS-c | 5-Amino-1MQ |
|---|---|---|
| Class | Mitochondrial-derived peptide | Small-molecule NNMT inhibitor |
| Primary research target | AMPK / metabolic homeostasis | NNMT enzyme |
| Research domain | Mitochondrial / metabolic | NAD+ / adipocyte metabolism |
| Structure | 16-residue peptide | Small molecule |
| Format | Lyophilized powder | Lyophilized powder |
MOTS-c in research
MOTS-c is a mitochondrial-derived peptide studied for its association with AMPK signaling and metabolic-homeostasis pathways in research models. See the full MOTS-c research profile.
5-Amino-1MQ in research
5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) studied in NAD+ and adipocyte-metabolism research models. See the full 5-Amino-1MQ research profile.
Key differences
- MOTS-c is a peptide acting in AMPK-associated pathways; 5-Amino-1MQ is a small molecule inhibiting NNMT.
- Both appear in metabolic research but via distinct mechanisms.
- MOTS-c is supplied as a lyophilized peptide; 5-Amino-1MQ as a lyophilized small-molecule compound.
Selecting for a research model
Researchers select between MOTS-c and 5-Amino-1MQ based on whether an AMPK-associated peptide or an NNMT-inhibitor mechanism fits the metabolic model. These distinctions are described strictly in the context of research models and are not statements of efficacy, safety, or suitability for any use.
Both MOTS-c and 5-Amino-1MQ ship from Vantage Aminos with a batch-specific Certificate of Analysis (HPLC purity and mass-spectrometry identity), U.S. synthesized for research use.
For research use only. Not for human or veterinary use.
- HPLC + MS tested, on tested lots
- U.S. synthesized
- Batch COA on the pages that carry one
